Jamie Lee Curtis and Jimmy Fallon Parody You Can See Everything

Jamie Lee Curtis and Jimmy Fallon debuted a deadpan parody of the documentary You Can See Everything on Wednesday night’s cold open of The Tonight Show Starring Jimmy Fallon, lampooning the viral interactions between Theranos founder Elizabeth Holmes and co-director Nathan Fielder.

Jamie Lee Curtis Channels Elizabeth Holmes in The Tonight Show Cold Open

Wednesday’s episode of The Tonight Show Starring Jimmy Fallon opened with a 90-second sketch that transported viewers straight into the awkward, protracted conversations of A24’s buzzy documentary You Can See Everything. Donning a blonde wig, guest Jamie Lee Curtis took on the persona of Elizabeth Holmes, while host Jimmy Fallon stepped into the role of Nathan Fielder, the documentary’s co-director who lived with Holmes during the month leading up to her imprisonment.

The sketch drew its premise directly from a central exchange in the film that also anchored its teaser trailer. Staring intently across the desk, Fallon delivered his best Fielder impression.

Now, be honest. Do you really want to be on the show tonight?

Jimmy Fallon, The Tonight Show

Curtis matched the intense gaze from the viral documentary clip before offering her response in a lowered, calculated voice. The dialogue faithfully recreated the film’s tense rhythm, with Fallon questioning whether she was merely there to promote a project or engaging as a human being.

Why would I deceive you? There’s no reason for me to do that. There’s nothing for me to deceive you on.

Jamie Lee Curtis, playing Elizabeth Holmes

When Fallon concluded the chat with a parting good chat and promised to see her out on the show, Curtis held the unblinking stare before he exited the room. The moment the door closed, she dropped the stiff facade, muttered an expletive, and yelled out in relief.

Theranos Documentary Becomes a Commercial and Critical Success

The late-night spoof arrives as the documentary itself continues a strong run at the box office. Directed by Fielder and Lance Oppenheim after more than three years of quiet production, You Can See Everything offers an unhinged look at the Theranos founder recorded a month before she began an 11-year prison sentence. A federal jury found Holmes guilty in January 2022 on four counts of defrauding investors, though she has consistently maintained her innocence.

In theaters, the slow-burn release has turned into a major commercial and critical success. The film grossed $19.5 million over its opening weekend and pulled in $45.1 million domestically after two weeks in release, establishing itself as the highest-grossing documentary at the domestic box office in 15 years.

Promotion for Newlyweds on NBC

While the cold open focused entirely on parodying the Theranos documentary, Curtis was a guest on the late-night program to promote her new NBC sitcom, Newlyweds, which premiered on Oct. 23. Created alongside Gail Lerner, the sitcom stars Téa Leoni and Tim Daly in a later-in-life love story about an impulsive marriage following a whirlwind courtship. Curtis appears in the series in a recurring guest star role.

Late-night television shows increasingly embrace the documentary's viral marketing moments. A month prior, Kate McKinnon brought her own take on Elizabeth Holmes to Late Night with Seth Meyers, re-enacting lines directly from the film’s trailer during her interview.