The Tampa Bay Buccaneers and Dallas Cowboys meet at AT&T Stadium on Thursday, October 8, 2026, for a Week 5 matchup airing on Amazon Prime Video at 8:15 p.m. ET. Dallas enters as a 9.5-point favorite while Tampa Bay searches for its first win behind an undrafted rookie quarterback.
The matchup at AT&T Stadium pits a struggling visiting squad against a Cowboys team trying to build momentum above the .500 mark. According to Pete Prisco’s Week 5 predictions, the home side is positioned to control the contest from early on.
No Baker Mayfield, no chance? Jalon Daniels did some nice things in his first start in NFL Week 4, but he is an undrafted rookie QB. Dak Prescott and Dallas will be able to outscore Tampa Bay to move above .500, while the Buccaneers will fall to 0-5.
Jeremy Cluff, via Azcentral
AT&T Stadium Betting Odds and Win Probabilities for Week 5
Betting markets list the Cowboys as a 9.5-point favorite over the Buccaneers. The over/under point total is set at 47.5 points.

Tampa Bay’s recent struggles continued prior to this trip. The Buccaneers took on more water on Sunday following a feeble 17-14 loss at home against Green Bay.
Dak Prescott and CeeDee Lamb Lead Dallas Offense Against Tampa Bay Defense
Dallas features prominent statistical leaders heading into the prime-time meeting. Teammate CeeDee Lamb paces the league with 498 receiving yards on 46 targets and 37 receptions, which both rank first in the NFL. Lamb is averaging 124.5 receiving yards and 9.3 catches per contest, while adding four receiving touchdowns, good for third in the league.
The visiting defense faces a heavy test against that aerial attack. Tampa Bay ranks ninth in the league in passing yards allowed with 817 total yards, translating to 204.3 yards per game, while allowing 16th in yards allowed per pass attempt with 6.6.
Bucky Irving Carries the Ground Attack for the Winless Buccaneers
On the other side of the ball, the Buccaneers rely on running back Bucky Irving, who leads the team with 241 rushing yards and one rushing touchdown while averaging 60.3 yards per game and 4.3 yards per carry, placing him 17th in the NFL.
The wider NFL slate features several other notable matchups and predictions across the league. Pete Prisco enters Week 5 looking to rebound after going 9-7 straight up and 4-11-1 against the spread the previous week due to late-game shenanigans and back-door covers. His overall season records sit at 38-26 straight up and 25-37-2 against the spread.
Other projections on the schedule include a London international series game where the Jacksonville Jaguars are picked to defeat a banged-up Philadelphia Eagles squad. The Eagles are dealing with significant injuries, including the retirement of right tackle Lane Johnson, which is expected to hinder their offense against Jacksonville’s stout scoring defense. In another contest, the Green Bay Packers are favored in an upset over the Chicago Bears as Jordan Love is anticipated to have a big day throwing the ball while the Bears play without Caleb Williams, whose absence could expose their ground-heavy attack.
Both the Houston Texans and Tennessee Titans enter their matchup at 0-4, with C.J. Stroud expected to make the plays late to lift the Texans to a 23-17 victory. Additional analyst predictions feature the Cincinnati Bengals overcoming receiver injuries—stemming from Tee Higgins and Ja’Marr Chase suffering injuries the previous week against the Jaguars—to defeat the Miami Dolphins, the New England Patriots capitalizing on a long trip for the Las Vegas Raiders, and the Minnesota Vikings utilizing a strong defense to outlast the New Orleans Saints 24-17.
The New York Jets are positioned to return home after two consecutive road games and pull off an upset over the 3-1 Cleveland Browns, who have won three straight. In other Sunday action, the Pittsburgh Steelers face the Indianapolis Colts, the Los Angeles Chargers host the Denver Broncos as the visitors play consecutive road games following a loss in San Francisco, the Detroit Lions and Arizona Cardinals square off in a potential shootout, and the Seattle Seahawks battle the San Francisco 49ers in a division clash. Wrapping up the weekly schedule, the Baltimore Ravens take on the Atlanta Falcons with potential Lamar Jackson injury concerns looming, and the Los Angeles Rams meet the Buffalo Bills on Monday night in a high-scoring affair where Matt Stafford and Josh Allen are expected to post big numbers before the Rams rally to claim a narrow win.